How much activity do guidelines suggest?
The World Health Organization’s physical activity guidance for adults is 150–300 minutes a week of moderate aerobic activity, or 75–150 minutes of vigorous activity, or a mix — plus muscle-strengthening activities that work all major muscle groups on 2 or more days a week. Some activity is better than none.[1]
For people on GLP-1 medicines, the 2025 joint advisory (ACLM, ASN, OMA, TOS) highlights resistance training and diet to preserve muscle and bone, and suggests assessing activity habits and strength at the start.[2]
What changes on a GLP-1 medicine?
- Eating less can leave you with less fuel; note how sessions feel on low-appetite days.
- Hydrate around exercise — the labels warn that vomiting or diarrhoea can lead to dehydration.[3][4]
- If you have diabetes and use insulin or a sulfonylurea, the labels warn of a higher risk of low blood sugar; ask how to adjust around exercise.[3][4]
- The Wegovy® label asks patients to tell their clinician about palpitations or a racing heartbeat at rest.[3]
What does PepLabo not do?
PepLabo does not create workout plans, set intensity limits or judge whether an exercise is safe for you. It records the sessions you do and shows them next to your doses.
Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S; Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company. They are named only to identify the medicines and their labels. PepLabo has no affiliation with these companies.
When to get help
| Sign | Who to contact | How fast | Source |
|---|---|---|---|
| Shakiness, sweating, confusion or a fast heartbeat if you have diabetes and use glucose-lowering medicine | Your prescriber | Today | Wegovy® §5.4, §17[3]; Zepbound® §5.7[4] |
| Vomiting or diarrhoea that does not go away, with dizziness | Your prescriber | Today | Wegovy® §5.5, §17[3] |
| A racing heartbeat or palpitations while at rest | Your prescriber | At your next appointment | Wegovy® §5.9, §17[3] |
